177.
COVID-19 Mental Disorders Collaborators,
Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic, 2021.10.08,
https://doi.org/10.1016/S0140-6736(21)02143-7 .
This article suggest that the pandemic has created an increased urgency to strengthen mental health systems in most countries. Mitigation strategies could incorporate ways to promote mental wellbeing and target determinants of poor mental health and interventions to treat those with a mental disorder. Taking no action to address the burden of major depressive disorder and anxiety disorders should not be an option.
176.
Daniel K Nomah, Juliana Reyes-Urueña, etc.,
Sociodemographic, clinical, and immunological factors associated with SARS-CoV-2 diagnosis and severe COVID-19 outcomes in people living with HIV: a retrospective cohort study, 2021.10.13,
https://doi.org/10.1016/S2352-3018(21)00240-X .
This study finds that people living with HIV with detectable HIV viraemia, chronic comorbidities, and some subpopulations could be at increased risk of severe outcomes from COVID-19. These groups should be prioritised in clinical management and SARS-CoV-2 vaccination programmes.
175.
Mark Philip Cassar, Elizabeth M. Tunnicliffe, etc.,
Symptom Persistence Despite Improvement in Cardiopulmonary Health – Insights from longitudinal CMR, CPET and lung function testing post-COVID-19. 2021.10.20,
https://doi.org/10.1016/j.eclinm.2021.101159 .
This study finds that cardiopulmonary abnormalities improve over time among patients, though some measures remain abnormal relative to controls. Persistent symptoms at 6 months post-COVID-19 did not associate with objective measures of cardiopulmonary health.
174.
Savino Sciascia, Piera Costanzo, etc.,
Safety and tolerability of mRNA COVID-19 vaccines in people with antiphospholipid antibodies, 2021.10.20,
https://doi.org/10.1016/S2665-9913(21)00320-9 .
This study finds that although more data are needed, including from long-term follow-up, immunogenicity data from their survey show that mRNA COVID-19 vaccines seem to have an acceptable safety and tolerability profile in patients with antiphospholipid antibodies. No major adverse effects nor thrombotic events were reported. Side-effects seem frequent, but mild and transient in nature.
173.
Kushalinii Hillson, Sue Costa Clemens, etc.,
Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination, 2021.10.21,
https://doi.org/10.1016/S0140-6736(21)02282-0 .
This study finds that fertility was unaffected by vaccination with ChAdOx1 nCoV-19. Furthermore, compared with women who received the control vaccine, there was no increased risk of miscarriage and no instances of stillbirth in women vaccinated before pregnancy in global clinical trials of ChAdOx1 nCoV-19.
172.
Esayas Kebede Gudina, Solomon Ali, etc.,
Seroepidemiology and model-based prediction of SARS-CoV-2 in Ethiopia: longitudinal cohort study among front-line hospital workers and communities, 2021.11.01,
https://doi.org/10.1016/S2214-109X(21)00386-7 .
This study finds that the SARS-CoV-2 spread in Ethiopia has been highly dynamic among hospital worker and urban communities. We can speculate that the greatest wave of SARS-CoV-2 infections is currently evolving in rural Ethiopia, and thus requires focused attention regarding health-care burden and disease prevention.
171.
Jane Achan, Asadu Serwanga, etc.,
Current malaria infection, previous malaria exposure, and clinical profiles and outcomes of COVID-19 in a setting of high malaria transmission: an exploratory cohort study in Uganda, 2021.10.25,
https://doi.org/10.1016/S2666-5247(21)00240-8 .
This study finds that although patients with COVID-19 with P falciparum co-infection had a higher frequency of confusion and vomiting, co-infection did not seem deleterious. The association between low previous malaria exposure and severe or critical COVID-19 and other adverse outcomes will require further study.
170.
Pritesh Lalwani, Christian A Ganoza, etc.,
High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort. 2021.11.01,
https://doi.org/10.1016/S2214-109X(21)00355-7 .
This study finds that an intense infection transmission period preceded the second wave of COVID-19 in Manaus. Several modifiable behaviours increased the risk of seroconversion, including non-compliance with non-pharmaceutical interventions measures such as not wearing a mask during contact, relaxation of protective measures, and non-remote working. Increased testing in high-transmission areas is needed to provide timely information about ongoing transmission and aid appropriate implementation of transmission mitigation measures.
169.
Gregory Milne, Thomas Hames, etc.,
Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity? 2021.10.21,
https://doi.org/10.1016/S2213-2600(21)00407-0 .
This article suggests that a protective immunological response lasts for approximately 5–12 months from primary infection, with reinfection being more likely given an insufficiently robust primary humoral response. Emerging data suggests that vaccine effectiveness might be reduced significantly against emerging variants of concern, and hence secondary vaccines will need to be developed to maintain population-level protective immunity. Nonetheless, other interventions will also be required, with further outbreaks likely to occur due to antigenic drift, selective pressures for novel variants, and global population mobility.
168.
Tapfumanei Mashe, Faustinos Tatenda Takawira, etc.,
Genomic epidemiology and the role of international and regional travel in the SARS-CoV-2 epidemic in Zimbabwe: a retrospective study of routinely collected surveillance data, 2021.10.22,
https://doi.org/10.1016/S2214-109X(21)00434-4 .
This article discovers that initial public health interventions delayed onset of SARS-CoV-2 community transmission after the introduction of the virus from international and regional migration in Zimbabwe. Global whole genome sequence data are essential to reveal major routes of spread and guide intervention strategies.
Chinese Society of International Law, in association with Chinese Institute of International Law at China Foreign Affairs University, and National Center for Foreign-related Rule of Law Research at China Foreign Affairs University
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