306. Yang Xia, Nancy Anderson, Increases in CLIA-Waived Testing Sites Since the Start of the COVID-19 Pandemic, 2023.01.13, https://academic.oup.com/labmed/advance-article/doi/10.1093/labmed/lmac154/6987228 . The number of testing sites receiving their first Certificate of Waiver (CoW) under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) increased significantly after the start of the COVID-19 pandemic. We compared the first-time CoWs in 2020–2021 to those in 2018–2019. The total number of first-time CoWs during 2020–2021 was more than twice what it was in 2018–2019, corresponding to population testing needs during the COVID-19 pandemic, especially in assisted living facility, pharmacy, physician office, and school/student health service settings.

305. Kun Xu, Chunxiang Fan, etc, Immunogenicity, efficacy and safety of COVID-19 vaccines: an update of data published by 31 December 2021, 2022.07.02, https://academic.oup.com/intimm/article/34/12/595/6627249 . Newly emerging variants, especially the variants of concern, and waning humoral responses pose serious challenges to the control of the COVID-19 pandemic. We summarized the humoral and cellular immunity, safety profiles and protection efficacy of COVID-19 vaccines with clinical data published by 21 May 2021. In this review, we summarize and update the published clinical data of COVID-19 vaccines and candidates up to 31 December 2021.

304. Manuel Serrano-Alarcón, Yuxi Wang, etc., The far-right and anti-vaccine attitudes: lessons from Spain’s mass COVID-19 vaccine roll-out, 2023.01.19, https://academic.oup.com/eurpub/advance-article/doi/10.1093/eurpub/ckac173/6992296?searchresult=1 . We show that public attitudes towards vaccination are not immutable. Whereas a rapid and effective vaccine rollout can help to overcome the resistance of far-right voters to get vaccinated, they also seem to be susceptible to their party leader’s discourse on vaccines.

303. Eric Yuk Fai Wan, Sukriti Mathur, etc., Association of COVID-19 with short- and long-term risk of cardiovascular disease and mortality: a prospective cohort in UK Biobank, 2023.01.19, https://academic.oup.com/cardiovascres/advance-article/doi/10.1093/cvr/cvac195/6987834 . COVID-19 infection, including long-COVID, is associated with increased short- and long-term risks of CVD and mortality. Ongoing monitoring of signs and symptoms of developing these cardiovascular complications post diagnosis and up till at least a year post recovery may benefit infected patients, especially those with severe disease.

302. Dana A Glei, The US Midlife Mortality Crisis Continues: Excess Cause-Specific Mortality During 2020, 2022.03.24, https://academic.oup.com/aje/article/191/10/1677/6553935 . Whether monthly excess mortality in the United States during 2020 varied by age and cause of death is investigated in this analysis. Drug-related deaths may be driving the increase in external mortality, but drug overdoses were already increasing for a full year before the pandemic. The oldest Americans bore the brunt of COVID-19 deaths, but working-age Americans, particularly men, suffered substantial numbers of excess non-COVID deaths, most commonly from external causes and heart disease.

301. Andrew Tiu, Zachary Susswein, etc., Characterizing the Spatiotemporal Heterogeneity of the COVID-19 Vaccination Landscape, 2022.04.27, https://academic.oup.com/aje/article/191/10/1792/6574722 . As variants of SARS-CoV-2 have emerged throughout 2021–2022, the need to maximize vaccination coverage across the United States to minimize severe outcomes of COVID-19 has been critical. Using a comparison with a mechanistic growth model fitted to our integrated data, we classified vaccination dynamics across time at the county scale. Our findings underline the importance of curating accurate, fine-scale vaccination data and the continued need for widespread vaccination in the United States, especially with the continued emergence of highly transmissible SARS-CoV-2 variants.

300. Mohammed Noushad, Mohammed Sadeg Al-Awar, etc., Lack of Access to Coronavirus Disease 2019 Vaccines Could Be a Greater Threat than Vaccine Hesitancy in Low-Income and Conflict Nations: The Case of Yemen, 2022.02.02, https://academic.oup.com/cid/article/75/10/1827/6520556 . We conducted a nation-wide cross-sectional survey among the general population in Yemen, a low-income conflict country. Overall, 50.1% of the 5329 respondents agreed to accept a COVID-19 vaccine and only 39.9% of participants agreed that they had access to a COVID-19 vaccine, with females indicating lower access than males. Overall, 50.1% of the 5329 respondents agreed to accept a COVID-19 vaccine. Only 39.9% of participants agreed that they had access to a COVID-19 vaccine, with females indicating lower access than males.

299. Saoussen Ben Abdallah, Yosra Mhalla, etc., Twice-Daily Oral Zinc in the Treatment of Patients With Coronavirus Disease 2019: A Randomized Double-Blind Controlled Trial, 2022.11.04, https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciac807/6795268?searchresult=1 . Zinc supplementation has been considered a potential therapy for COVID-19. We aimed to examine zinc efficacy in adult patients with COVID-19 infection. We conducted a prospective, randomized, double-blind, placebo-controlled multicenter trial, and found that, in COVID-19 patients, oral zinc can decrease 30-day death, ICU admission rate and can shorten symptom duration.

298. Faris Chalali, Marie Merlant, etc., Histological Features Associated With Human Monkeypox Virus Infection in 2022 Outbreak in a Nonendemic Country, 2022.11.01, https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciac856/6787607 . Skin histology of papules and pustules from 5 men having sex with men with Monkeypox infection showed viral intracytoplasmic cytopathic changes, interface dermatitis, marked inflammatory dermic infiltrate including superficial neutrophils and perivascular and periadnexal deep lymphocytes. Histologic description of Monkeypox lesions improves our understanding about clinical presentations and may have some therapeutic implications.

297. Ann E Woolley, Scott Dryden-Peterson, etc., At-home Testing and Risk Factors for Acquisition of SARS-CoV-2 Infection in a Major US Metropolitan Area, 2022.10.05, https://academic.oup.com/ofid/article/9/11/ofac505/6748960 . Unbiased assessment of the risks associated with acquisition of SARS-CoV-2 is critical to informing mitigation efforts during pandemics. The objective of our study was to understand the risk factors for acquiring COVID-19 in a large prospective cohort of adult residents in a large US metropolitan area. These results demonstrate that race/ethnicity and socioeconomic status are the biggest determinants of acquisition of infection.

Chinese Society of International Law, in association with Chinese Institute of International Law at China Foreign Affairs University, and National Center for Foreign-related Rule of Law Research at China Foreign Affairs University
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