327. Changwoo Han, Changes in mortality rate of the general population during the COVID-19 pandemic: an interrupted time series study in Korea, 2022.04.23, https://academic.oup.com/ije/article/51/5/1396/6573377 . The non-accidental mortality rate in South Korea for the first year of the pandemic followed the historical trends. However, there was a decrease in mortality associated with respiratory diseases, and an increase in mortality occurring outside of medical facilities. The findings may be attributed to changes in public behaviours, and availability of medical resources during the pandemic.

326. Florian Poydenot, Ismael Abdourahamane, etc., Risk assessment for long and short range airborne transmission of SARS-CoV-2, indoors and outdoors, 2022.10.06, https://academic.oup.com/pnasnexus/advance-article/doi/10.1093/pnasnexus/pgac223/6750016?searchresult=1 . The dispersion cone leads to a concentration in viral particles, and therefore a short range transmission risk, inversely proportional to the squared distance to an infected person and to the flow velocity. The aerosolization criterion derived as an intermediate result, which compares the Stokes relaxation time to the Lagrangian time scale, may find application for a broad class of aerosol-borne pathogens and pollutants.

325. Courtney D Segal, William B Lober, etc., Trading-off privacy and utility: the Washington State experience assessing the performance of a public health digital exposure notification system for coronavirus disease 2019, 2022.10.07, https://academic.oup.com/jamia/advance-article/doi/10.1093/jamia/ocac178/6752071?searchresult=1 . DEN systems were an emergency response to COVID-19 pandemic, harnessing smartphone-based technology to enhance conventional pandemic response strategies such as contact tracing. We use implementation science to frame the evaluation of DEN tools by linking the theoretical constructs with the metrics available in the underlying disparate, deidentified, and aggregate data infrastructure. Continued collaboration and multidisciplinary consensus activities can improve the utility of DEN tools for future public health emergencies.

324. Neal Doran, Jenna Gress-Smith, etc., Suicide Risk Among Military Veterans in the Southwestern United States Before and During the COVID-19 Pandemic, 2022.10.13, https://academic.oup.com/milmed/advance-article/doi/10.1093/milmed/usac303/6759407?searchresult=1 . The pandemic has not led to an increase in suicidal behavior, which is consistent with other studies, although the degree of decline varied across diagnostic and demographic groups. Further longitudinal research is needed to evaluate whether the prolonged nature of COVID-19 may lead to changes in risk over time.

323. Maj Britt Dahl Nielsen, Ola Ekholm, etc., Mental wellbeing among Danish employees during the COVID-19 pandemic: results from a longitudinal study on the role of industry and working environment, 2022.10.13, https://academic.oup.com/eurpub/advance-article/doi/10.1093/eurpub/ckac150/6760677?searchresult=1 . Mental wellbeing declined among employees in all industries with no difference between industries. Employees working from home may have been particularly vulnerable, and the analyses show that managers play a key role in mitigating the negative consequences of the pandemic by ensuring adequate information and involvement of employees.

322. Preeti Pushpalata Zanwar, Arokiasamy Perianayagam, etc., Examining the Impacts of Coronavirus Disease 2019 Mitigation Policies on Health Outcomes of Older Adults: Lessons Learned From Six High-Income or Middle-Income Countries, 2022.10.09, https://academic.oup.com/ppar/advance-article/doi/10.1093/ppar/prac023/6754345?searchresult=1 . There were considerable differences in COVID-19 mitigation and control policies in countries that used a centralized, top-down approach (Japan, India) versus those that used a decentralized, bottom-up approach (Canada, the United States, Brazil, Russia) with unique within-country aspects. The pandemic magnified the existing health-care disparities among disadvantaged populations and the lack or underfunding of public health infrastructures across several countries. We recommend investments in developing and strengthening public health infrastructures, coordination with homeland security, and building modern health data ecosystems for future pandemic emergency preparedness.

321. Waasila Jassat, Prof Salim S Abdool Karim, etc., Clinical severity of COVID-19 in patients admitted to hospital during the omicron wave in South Africa: a retrospective observational study, 2022.05.18, https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(22)00114-0/fulltext . Up to the end of January, 2022, South Africa has had four recognisable COVID-19 pandemic waves, each predominantly dominated by one variant of concern: the ancestral strain with an Asp614Gly mutation during the first wave, the beta variant (B.1.351) during the second wave, the delta variant (B.1.617.2) during the third wave, and lastly, the omicron variant (B.1.1.529) during the fourth wave. We aimed to assess the clinical disease severity of patients admitted to hospital with SARS-CoV-2 infection during the omicron wave and compare the findings with those of the preceding three pandemic waves in South Africa.

320. Nicolas Veyrenche, Amandine Pisoni, etc., Severe Acute Respiratory Syndrome Coronavirus 2 Nucleocapsid Antigen in Urine of Hospitalized Patients With Coronavirus Disease 2019, 2022.05.01, https://academic.oup.com/jid/article/226/5/812/6540163 . SARS-CoV-2 N-Ag can be detected in the blood of patients with COVID-19. We used a highly sensitive and specific assay to explore the presence of N-Ag in urine during the course of COVID-19 and its relationship with the severity of disease.We studied urinary and plasma N-Ag using a highly sensitive immunoassay in 82 patients with SARS-CoV-2 infection proved by polymerase chain reaction. Our study demonstrates that N-Ag is present in the urine of patients hospitalized in the early phase of COVID-19. As a direct marker of SARS-CoV-2, urinary N-Ag reflects the dissemination of viral compounds in the body. Urinary N-Ag may be a useful marker for disease severity in SARS-CoV-2 infections.

319. Yasushi Tsujimoto, Masanori Kobayashi, etc., Outcomes in novel hospital-at-home model for patients with COVID-19: a multicentre retrospective cohort study, 2023.01.01, https://academic.oup.com/fampra/advance-article/doi/10.1093/fampra/cmad010/7022079?searchresult=1 . Hospital-at-home (HaH) care has been proposed as an alternative to inpatient care for patients with COVID-19. We conducted a multicentre retrospective cohort study of the COVID-19 patients who received our HaH care from 1 January to 31 March 2022. The HaH care model with a team of primary care clinics was able to triage patients with COVID-19 who needed immediate hospitalization without involving hospitals, and treated most of the remaining patients at home.

318. Madhu Jalan, Kira Riehm, etc, Burden of mental distress in the US associated with trust in media for COVID-19 information, 2022.11.21, https://academic.oup.com/heapro/article/37/6/daac162/6835391 . Trust in different news outlets may be associated with mental distress during public health emergencies like the COVID-19 pandemic. Future studies should explore mechanisms behind these associations, including adherence to best practices for crisis reporting among different media sources and exposure of individuals to misinformation.

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