A Lianne Messchendorp , Ron T Gansevoort,
Vaccinated kidney transplant recipients are yet not sufficiently protected against COVID-19, 2023.06.27,
Although the whole world was waiting for a vaccine to become available, these data make clear that an effective and safe vaccine was especially crucial for patients with kidney failure. We hope that (temporarily) changing MMF/MPA into everolimus around vaccination will result in improved protection against disease.
Multi-omics in COVID-19: Driving development of therapeutics and vaccines, 2023.05.30,
The ongoing COVID-19 pandemic caused by SARS-CoV-2 has raised global concern for public health and the economy. The development of therapeutics and vaccines to combat this virus are continuously progressing. Here, we provide an up-to-date overview of the latest applications of multi-omics technologies in strategies addressing COVID-19, in order to provide suggestions towards the development of highly effective knowledge-based therapeutics and vaccines.
Lack of Hepatitis C Virus Elimination by 2030 in Los Angeles County at Current Treatment Rate, 2023.03.10,
The time is now for the United States to go beyond testing and linkage to care and implement effective approaches that integrate publicly funded treatment activities to accelerate HCV elimination. Los Angeles County is primed for leveraging the existing case-reporting and public health management approach. Further investments and public health efforts are necessary; otherwise the goal of HCV elimination by 2030 will remain elusive.
Andrea Marzi , Heinz Feldmann,
Marburg Virus Disease: Global Threat or Isolated Events? 2023.05.15,
The recent emergence of Marburg virus in new geographical locations such as Guinea, Ghana, Equatorial Guinea, and Tanzani, is raising public health concern and media attention to Marburg virus disease. Here, we briefly summarize the current status of the outbreak response and countermeasure development.
Munira Ratansi , Anthony R Cox,
A prospective investigational study of vitamin D status in patients with hospital-acquired pneumonia, 2023.05.16,
Hospital-acquired pneumonia (HAP) is the most common healthcare-associated infection (HCAI) contributing to death. Rising antimicrobial resistance has resulted in few effective antibiotics for HAP. Vitamin D deficiency was highly prevalent in the HAP participants. Vitamin D deficiency was also present in some participants, despite prescribed prophylactic supplementation. Vitamin D stimulates immunity and hence vitamin D deficiency would have potentially increased the susceptibility of acquiring HAP.
Andrea Marzi ,
Preexisting immunity does not prevent efficacy of VSV-based filovirus vaccines in nonhuman primates, 2023.06.08,
Ebola virus (EBOV) and Marburg virus (MARV) made headlines in the past decade causing outbreaks of human disease in previously nonendemic yet overlapping areas. While EBOV outbreaks can be mitigated with licensed vaccines and treatments, there is not yet a licensed countermeasure for MARV. This study again demonstrates that VSVΔG-based filovirus vaccine can be successfully used in individuals with pre-existing VSV vector immunity highlighting the platform’s applicability for consecutive outbreak response.
Increased rhinovirus/enterovirus infections including Ev-D68 in the United States, a challenge for healthcare providers amidst influenza virus infection and the COVID-19 pandemic, 2023.02.25,
This editorial discusses the increased Rhinovirus/Enterovirus infections in the United States, challenges faced by healthcare providers and provides recommendations to address the issue.
Negligible risk of surface transmission of SARS-CoV-2 in public transportation, 2023.05.03,
Our findings suggest that surface transmission played no or negligible role in spreading SARS-CoV-2 in Prague. The results also demonstrate the potential of the new biosensor to serve as a complementary screening tool in epidemic monitoring and prognosis.
Transmission of SARS-CoV-2 among recruits in a US Army training environment: a brief report, 2023.05.03,
In 2020, preventive measures were implemented to mitigate the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among 600–700 recruits arriving weekly at a basic combat training (BCT) facility in the southern United States. Nonpharmaceutical measures, such as masking, and social distancing, were maintained throughout quarantine and BCT. We assessed for SARS-CoV-2 transmission in the quarantine milieu.
Travel-related respiratory symptoms and infections in travellers (2000–2022): a systematic review and meta-analysis, 2023.06.13,
Respiratory tract infections (RTIs) are common in travellers due to the year-round or seasonal presence of respiratory pathogen and exposure to crowded environments during the itinerary. The aim of this systematic review and meta-analysis is to evaluate the prevalence of RTIs and symptoms suggestive of RTIs among travellers according to risk groups and/or geographic region, and to describe the spectrum of RTIs.
Beijing Interest Group on Global Health and Global Governance