171. Jane Achan, Asadu Serwanga, etc., Current malaria infection, previous malaria exposure, and clinical profiles and outcomes of COVID-19 in a setting of high malaria transmission: an exploratory cohort study in Uganda, 2021.10.25, https://doi.org/10.1016/S2666-5247(21)00240-8 . This study finds that although patients with COVID-19 with P falciparum co-infection had a higher frequency of confusion and vomiting, co-infection did not seem deleterious. The association between low previous malaria exposure and severe or critical COVID-19 and other adverse outcomes will require further study.

170. Pritesh Lalwani, Christian A Ganoza, etc., High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort. 2021.11.01, https://doi.org/10.1016/S2214-109X(21)00355-7 . This study finds that an intense infection transmission period preceded the second wave of COVID-19 in Manaus. Several modifiable behaviours increased the risk of seroconversion, including non-compliance with non-pharmaceutical interventions measures such as not wearing a mask during contact, relaxation of protective measures, and non-remote working. Increased testing in high-transmission areas is needed to provide timely information about ongoing transmission and aid appropriate implementation of transmission mitigation measures.

169. Gregory Milne, Thomas Hames, etc., Does infection with or vaccination against SARS-CoV-2 lead to lasting immunity? 2021.10.21, https://doi.org/10.1016/S2213-2600(21)00407-0 . This article suggests that a protective immunological response lasts for approximately 5–12 months from primary infection, with reinfection being more likely given an insufficiently robust primary humoral response. Emerging data suggests that vaccine effectiveness might be reduced significantly against emerging variants of concern, and hence secondary vaccines will need to be developed to maintain population-level protective immunity. Nonetheless, other interventions will also be required, with further outbreaks likely to occur due to antigenic drift, selective pressures for novel variants, and global population mobility.

168. Tapfumanei Mashe, Faustinos Tatenda Takawira, etc., Genomic epidemiology and the role of international and regional travel in the SARS-CoV-2 epidemic in Zimbabwe: a retrospective study of routinely collected surveillance data, 2021.10.22, https://doi.org/10.1016/S2214-109X(21)00434-4 . This article discovers that initial public health interventions delayed onset of SARS-CoV-2 community transmission after the introduction of the virus from international and regional migration in Zimbabwe. Global whole genome sequence data are essential to reveal major routes of spread and guide intervention strategies.

167. Wingel Xue, Alexandre White, COVID-19 and the rebiologisation of racial difference, 2021.10.23, https://doi.org/10.1016/S0140-6736(21)02241-8 . This article elaborates the initial impulse of pandemic rumours regarding Black immunity to SARS-CoV-2 infection that attribute disparities to biological difference which is conferred by racial typology and highlights the enduring power of race-thinking.

166. Clifford Stott, Matt Radburn, etc., Police Powers and Public Assemblies: Learning from the Clapham Common ‘Vigil’ during the Covid-19 Pandemic, 2021.10.21, https://doi.org/10.1093/police/paab060 . This article provides a analysis of the policing operation surrounding a highly controversial public assembly and discusses the implications of their analysis for understanding the inherent dangers of regulatory frameworks that place too heavy a burden of discretionary power into the hands of police in determining whether public assemblies are ‘lawful’, and under what conditions they can occur.

165. Xinyuan Ye, Exploring the relationship between political partisanship and COVID-19 vaccination rate, 2021.10.23, https://doi.org/10.1093/pubmed/fdab364 . This study examines the association between the political partisanship and vaccination rate at the county-level and quantifies the differences between the Democratic and Republican parties.

164. Kirsten R Palmer, Michael Tanner, etc.,, Widespread implementation of a low-cost telehealth service in the delivery of antenatal care during the COVID-19 pandemic: an interrupted time-series analysis, 2021.07.03, https://doi.org/10.1016/S0140-6736(21)00668-1 . This study finds that telehealth integrated antenatal care enabled the reduction of in-person consultations by 50% without compromising pregnancy outcomes. This care model can help to minimise in-person interactions during the COVID-19 pandemic, but should also be considered in post-pandemic health-care models.

163. Mine Durusu Tanriover, Hamdi Levent Doğanay, etc., , Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in Turkey, 2021.07.08 , https://doi.org/10.1016/S0140-6736(21)01429-X . This study finds that CoronaVac has high efficacy against PCR-confirmed symptomatic COVID-19 with a good safety and tolerability profile.

162. Thomas M Drake, Aya M Riad, etc.,, Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study, 2021.07.17,, https://doi.org/10.1016/S0140-6736(21)00799-6 . This study finds that complications and worse functional outcomes in patients admitted to hospital with COVID-19 are high, even in young, previously healthy individuals. Acute complications are associated with reduced ability to self-care at discharge, with neurological complications being associated with the worst functional outcomes. COVID-19 complications are likely to cause a substantial strain on health and social care in the coming years. These data will help in the design and provision of services aimed at the post-hospitalisation care of patients with COVID-19.

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