492. Gila Lustig, Yashica Ganga, Hylton E Rodel et al., SARS-CoV-2 infection in immunosuppression evolves sub-lineages which independently accumulate neutralization escape mutations, 2023.12.28, https://doi.org/10.1093/ve/vead075 . This article finds that SARS-CoV-2 strains in prolonged infection in a single individual can follow independent evolutionary trajectories which lead to neutralization escape and other changes in viral properties.

491. Christina Marini, Erin Basinger, Meagan Stewart et al., Forecasting the Future: Older Adults’ Anticipated Stressors and Rewards in the Context of Covid-19, 2023.12.21, https://doi.org/10.1093/geroni/igad104.0241 . This study highlights variability in the events older adults were concerned and excited about within and across timepoints. Salience of the pandemic as an anticipated stressor ebbed and flowed alongside emerging variants, despite vaccine availability.

490. Ashley Stark, Daniel K Benjamin, Anthony Kajencki et al., School Absenteeism as a Marker for Community COVID-19 Rates, 2023.12.23, https://doi.org/10.1093/jpids/piad072 . This study finds that student absenteeism and infection rates may be a useful marker of COVID-19 community infection rates when testing frequency and results reporting are inconsistent.

489. Christine So, Katherine Fiori, Amy Rauer, etc., The Costs of Generativity for Older Adults’ Mental Health During the Covid-19 Pandemic, 2023.12.21, https://doi.org/10.1093/geroni/igad104.0240 . This study underscores the complexity of the role of generativity in mental health outcomes, with associations sensitive to historical events.

488. Heather Fuller, Andrea Huseth-Zosel, Emily Kinkade et al., Patterns and Themes of Older Adults’ Coping Across Two Years of the Covid-19 Pandemic, 2023.12.21, https://doi.org/10.1093/geroni/igad104.0242 . This study finds that older adults had nuanced and shifting coping experiences throughout the initial two years of the pandemic, but overall coped by drawing on life experiences.

487. Nneka M Chika-Igwenyi, Uche S Unigwe, Nnennaya A Ajayi et al., Atypical Mpox in a Nigerian Tertiary Health Facility, 2023.12.29, https://doi.org/10.1093/infdis/jiad607 . This article highlights the need for further evaluation of unusual skin lesions and inclusion of mpox screening for genital skin lesions presumed STI. Revision of clinical case definition and enhanced surveillance is key to early recognition and prevention of spread.

486. Darly Dash, Fabrice I Mowbray, Jeffrey W Poss et al., The association between frailty, long-term care home characteristics and COVID-19 mortality before and after SARS-CoV-2 vaccination: a retrospective cohort study, 2023.12.30, https://doi.org/10.1093/ageing/afad229 . This article finds that frailty is consistently associated with COVID-19 mortality before and after the availability of SARS-CoV-2 vaccination. Home-level characteristics previously attributed to COVID-19 outcomes do not explain significant home-to-home variation in COVID-19 mortality.

485. Camila Carlos Bezerra, Noeli das Neves Toledo, Sonia Maria Dozzi Brucki et al., COVID-19 and Cognitive and Mental Health during Post-Infection Phase: A Study Among Middle-Aged and Older Indigenous Adults from Brazilian Amazons, 2023.12.29, https://doi.org/10.1093/geronb/gbad197 . This study aims to examine the rate of self-reported COVID-19 and its association with mental and cognitive health during the post-infection phase among middle-aged and older indigenous adults.

484. Noah Kojima, Christopher A Taylor, Mark W Tenforde et al., Clinical outcomes of U.S. adults hospitalized for COVID-19 and influenza in the Respiratory Virus Hospitalization Surveillance Network, October 2021-September 2022, 2023.12.30, https://doi.org/10.1093/ofid/ofad702 . This study finds that severe outcomes were common among adults hospitalized for COVID-19 or influenza, while the percentage of COVID-19 hospitalizations involving critical care decreased from 10/2021 to 9/2022. During the Omicron BA.5 period, ICU admission frequency was similar for COVID-19 and influenza, though COVID-19 patients had a higher frequency of in-hospital death.

483. Kathy O Lui, Zhangjing Ma, Stefanie Dimmeler, SARS-CoV-2 induced vascular endothelial dysfunction: direct or indirect effects?, 2023.12.30, https://doi.org/10.1093/cvr/cvad191 . This study reviews latest research on endothelial ACE2 expression in different vascular beds, and the heterogeneity in various EC subsets with differential ACE2 expression in response to SARS-CoV-2.

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